NO INCREASE IN URINE LEAKING

Impact of hysterectomy on stress urinary incontinence: an identical twin study

This research was presented at the 32nd Annual Scientific Meeting of the International Urogynecological Association, Cancun, Mexico, June 12-16, 2007, and the 28th Annual Scientific Meeting of the American Urogynecologic Society, Hollywood, FL, Sept. 27-29, 2007.

Jay-James R. Miller, MD, MSaCorresponding Author Informationemail address, Sylvia M. Botros, MD, MSb, Jennifer L. Beaumont, MSc, Sarit O. Aschkenazi, MDb, Tondalaya Gamble, MD, MPHb, Peter K. Sand, MDb, Roger P. Goldberg, MD, MPHb

Received 2 August 2007; received in revised form 19 November 2007; accepted 24 January 2008.

Objective

This study uses the unique properties of twin research design to evaluate whether hysterectomy impacts stress urinary incontinence (SUI).

Study Design

As part of the Evanston Twins Sister Study, we performed bivariate and multivariate analyses on 83 identical twin pairs discordant for hysterectomy.

Results

In bivariate analysis, SUI was less common in women who had prior hysterectomy (P =0.028). Multivariate analysis suggested that SUI was significantly less common after hysterectomy (odds ratio [OR], 0.55, confidence interval [CI], 0.30 to 1.00). Exclusion of twin pairs with a history of pelvic floor defect surgery eliminated the statistical relationship between hysterectomy and SUI (OR, 0.79, CI, 0.4 to 1.40).

CONCLUSION

Hysterectomy, when analyzed with all cases, was associated with reduced SUI. When concurrent pelvic floor defect surgeries were excluded from the analysis, we found NO RELATIONSHIP between hysterectomy and the risk of SUI afterward.

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